4 . Skin Sensitisation
نویسندگان
چکیده
Rules related to the safety of cosmetic products are imposed by the Council Directive 76/768/EEC (Cosmetics Directive) of 27 July 1976 (with subsequent amendments and adaptations). Article 2 states that: "A cosmetic product put on the market within the Community must not cause damage to human health when applied under normal or reasonably foreseeable conditions of use ..." Article 7 explains that "... the manufacturer shall take into consideration the general toxicological profile of the ingredient, its chemical structure and its level of exposure."
منابع مشابه
For Skin sensitisation test method site: Skin sensitisation TITLE OF THE TEST GUIDELINES (YEAR OF APPROVAL): In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA), OECD 442C
TITLE OF THE TEST GUIDELINES (YEAR OF APPROVAL): In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA), OECD 442C (adopted 2015) In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method, OECD 442D (adopted 2015) In Vitro Skin Sensitisation: Human Cell Line Activation Test (h-CLAT) (draft OECD TG under discussion, EURL ECVAM recommendation published 2015) In vivo tests: Skin ...
متن کاملGlobal QSAR models of skin sensitisers for regulatory purposes
BACKGROUND The new European Regulation on chemical safety, REACH, (Registration, Evaluation, Authorisation and Restriction of CHemical substances), is in the process of being implemented. Many chemicals used in industry require additional testing to comply with the REACH regulations. At the same time EU member states are attempting to reduce the number of animals used in experiments under the 3...
متن کاملSensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study
BACKGROUND German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in...
متن کاملThe association of month of birth with atopy in adult patients with asthma and rhinitis in Anatolia, Turkey.
BACKGROUND Exposure to allergens in early life may predispose subjects to develop allergies and diseases related to allergic sensitisation. OBJECTIVE To determine the association between month of birth and atopic sensitisation in adult Turkish patients with rhinitis and/or asthma using the diagnostic method of skin prick tests. METHODS This prospective cross-sectional study included all adu...
متن کاملSensitization profiles in polysensitized patients from a restricted geographical area: further lessons from multiplexed component resolved diagnosis.
BACKGROUND The micro-array techniques for the detection of specific IgE has improved the diagnostic procedures for allergic diseases. This method also allows to define sensitisation profiles from an epidemiological point of view. We studied the sensitisation pattern in a population of polysensitized patients with respiratory allergy, living in a restricted geographical area in the north-west It...
متن کاملAssociation of sensitization to food and inhalant allergens in patients of asthma and rhinitis
Results Of 1860 patients screened, 1097 (58.9 %) gave history of food allergy. Of the history positive patients 470 were skin prick tested . 29.3 % (138/470) exhibited positive reactions to one or more food(s). Rice elicited SPT positive reaction in maximum ( 6.2 %) cases followed by blackgram (5.9 %), lentil (5.5 %), citrus fruits (5.3 %), pea (3.8 %), maize (3.8%) and banana (3.6 %). Among fo...
متن کامل